Thursday, April 10, 2014

The facts will kill you

So since we got the go-ahead to trigger I've been obsessing over researching IUI statistics.

And generally driving myself crazy.

To recap: 1 blocked tube, borderline motility, 4% morphology, and annovulatory cycles.

So I keep finding research that gives me hope. Not all of my source links direct straight to the research. I apologize.

So there are things I find that make me smile.... Like this:

"The pregnancy rate per cycle was similar, 17.3% for the unilateral tubal occlusion group and 16.5% for the unexplained infertility group. The rate of miscarriage (11.1% vs. 23.3%) and ectopic pregnancy (11.1% vs. 6.7%) was similar between the two groups. The pregnancy rate was higher in patients with proximal occlusion (25.0%) compared with distal occlusion (13.9%) or unexplained infertility, but not statistically significant."  (SOURCE)

Or these:

Four follicles IUI: Success rate of 23% (SOURCE
Number of cycles: IUI success rates are highest in first one or two cycles depending on study (SOURCE)
And even tips for increasing IUI success rates like these:
  • Try progesterone luteal phase support: boosts IUI success rate from 14% to 24%, 13% to 21%, 6% to 19%
  • Perform IUI on a full bladder: boosts success rate from 7% to 14%
  • Perform IUI using ultrasound guidance: boosts success rate from 14% to 23%
  • Minimize abstinence period before sperm collection to 2 days or less: boosts IUI success rate from 3% to 14%
Of course there are the scarier studies about the risk of multiples (and Higher Order Multiples)

  • For age <32 years, HOMP was 6% for three to six follicles and 20% for seven or more follicles (SOURCE) 
  • Approximately 30% of pregnancies resulting from gonadotropins are multiples. While most of these pregnancies are twins, up to 5% are triplets or greater due to the release of more eggs than expected. (SOURCE)

So I've concluded that I'm looking at a 20%ish chance of pregnancy this cycle, and if we're pregnant, a 1 in 4 chance of twins or more.

So there's no point in stressing. The horse is out of the barn, and what is meant to happen will happen. 

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